Phyto-composition and Antimicrobial Activities of the Ethanol Seed Extracts of Buchholzia Coriacea

Abstract

Background: There is a growing awareness in correlating phytochemical compounds with their biological activities. Folk medicines suggest that Bulccholzia coriacea is effective in the management of bacterial infections.

Objectives: This research was aimed at investigating the phyto-composition and antimicrobial activities of Bulccholzia coriacea ethanol seed extract.

Methods: Phyto-composition of Bulccholzia coriacea seeds were determined using gas chromatography mass spectroscopy (GC-MS) technique. Clinical isolates; Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Klebsiella pneumonia, Streptococcus faecalis, and Candida albicans were used to test for the antimicrobial activities of Bulccholzia coriacea seeds following disc diffusion and broth dilution methods.

Results: Gas chromatogram reveal six peaks depicting different phyto-constituents with Oleic acid (75.57%) highest peaked. Candida albican, Staphylococcus epidermidis, Klebsiella pneumonia and Staphylococcus aureus had the same minimum inhibitory concentration (MIC) value of 6.25mg/ml and minimum bactericidal concentration (MBC) value of 12.5mg/ml.

Conclusion: Findings from this study supports the claims of local people who use B. coriacea seeds for the management of infectious diseases.